Problem 3

Gene filtering on B-cell ALL patients We work with the patients in stages "B2","B3".

(a) We look for genes expressed differently in stages B2 and B3. Use genefilter to program the Wilcoxon test and the Welch t-test separately for each gene. For each test, we select the genes with p-value<0.001 . use exact=F in the wilcoxon test function.

(b) Compute a Venn diagram for the wilcoxon test and the t-test, and plot it.

(c) How many pass the wilcoxon filter? How many passes both filters?

(d) what is the annotation package for the ALL data set? Find the GO numbers for "oncogene"

(e) How many genes passing the filters in (a) are oncogenes?

Subject | Mathematics |

Due By (Pacific Time) | 11/15/2015 08:36 pm |

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